Suspension of Isoniazid Formulated Using Cationic Resin for Pediatric Use
نویسندگان
چکیده
The purpose of this research was to develop and evaluate pediatric formulation by masking the bitter taste of Isoniazid.Non-compliance of therapy of tuberculosis which is mostly associated with bitter taste can lead to worsening of diseased condition in children. Cationic resin utilized to mask the bitter taste of Isoniazidby preparing resinate complex. Syrup preparation evaluated for drug content, in vitro drug release, viscosity, taste masking, Infra red spectroscopic studyand stability study. Ion exchange resin method using KYRON T-134 proved as a alternative method to prepare suitable pediatric formulation.
منابع مشابه
Reconstituted powder for suspension of antitubercular drugs formulated as microspheres for pediatric use.
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